Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4 		0.300 Biomarker phenotype CTD_human The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice. 15275829 2004
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3 		0.300 Biomarker phenotype CTD_human The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice. 15275829 2004
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.300 Therapeutic phenotype CTD_human Systemic morphine blocks the seizures induced by intracerebroventricular (i.c.v.) injections of opiates and opioid peptides. 7127082 1982
Entrez Id: 5443
Gene Symbol: POMC
POMC 		0.300 Biomarker phenotype CTD_human Systemic morphine blocks the seizures induced by intracerebroventricular (i.c.v.) injections of opiates and opioid peptides. 7127082 1982
Entrez Id: 5020
Gene Symbol: OXT
OXT 		0.300 Biomarker phenotype CTD_human Syntocinon induced convulsion. 5493616 1970
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.300 Biomarker phenotype CTD_human Stimulation of 5-HT 1A receptors increases the seizure threshold for picrotoxin in mice. 16313900 2005
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.300 Therapeutic phenotype CTD_human Stimulation of 5-HT 1A receptors increases the seizure threshold for picrotoxin in mice. 16313900 2005
Entrez Id: 57534
Gene Symbol: MIB1
MIB1 		0.300 Biomarker phenotype CTD_human Spontaneous seizures and altered gene expression in GABA signaling pathways in a mind bomb mutant zebrafish. 20943912 2010
Entrez Id: 2353
Gene Symbol: FOS
FOS 		0.300 Biomarker phenotype CTD_human Spontaneous recurrent seizures after pilocarpine-induced status epilepticus activate calbindin-immunoreactive hilar cells of the rat dentate gyrus. 11955713 2002
Entrez Id: 2353
Gene Symbol: FOS
FOS 		0.300 Biomarker phenotype CTD_human Spatial and temporal evolution of neuronal activation, stress and injury in lithium-pilocarpine seizures in adult rats. 9630518 1998
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker phenotype CTD_human Some endorphin derivatives and hydrocortisone prevent EEG limbic seizures induced by corticotropin-releasing factor in rabbits. 1700951 1991
Entrez Id: 7248
Gene Symbol: TSC1
TSC1 		0.300 Biomarker phenotype CTD_human Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia. 28215400 2017
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		0.300 Biomarker phenotype CTD_human Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia. 28215400 2017
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Therapeutic phenotype CTD_human Sigma 1 receptor-mediated increase in hippocampal extracellular dopamine contributes to the mechanism of the anticonvulsant action of neuropeptide Y. 18005069 2007
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Biomarker phenotype CTD_human Sigma 1 receptor-mediated increase in hippocampal extracellular dopamine contributes to the mechanism of the anticonvulsant action of neuropeptide Y. 18005069 2007
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7 		0.300 Biomarker phenotype CTD_human Sensitivity to the seizure-inducing effects of nicotine is associated with strain-specific variants of the alpha 5 and alpha 7 nicotinic receptor subunit genes. 9495872 1998
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5 		0.300 Biomarker phenotype CTD_human Sensitivity to the seizure-inducing effects of nicotine is associated with strain-specific variants of the alpha 5 and alpha 7 nicotinic receptor subunit genes. 9495872 1998
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1 		0.300 Biomarker phenotype CTD_human Seizures and extrapyramidal symptoms in a patient with Tourette's syndrome, Asperger's syndrome, and multiple sclerosis treated with interferon beta-1a and clomipramine. 12432978 2002
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Biomarker phenotype CTD_human Seizure susceptibility of neuropeptide-Y null mutant mice in amygdala kindling and chemical-induced seizure models. 15451008 2004
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Therapeutic phenotype CTD_human Seizure susceptibility of neuropeptide-Y null mutant mice in amygdala kindling and chemical-induced seizure models. 15451008 2004
Entrez Id: 1128
Gene Symbol: CHRM1
CHRM1 		0.300 Biomarker phenotype CTD_human Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine-induced seizure activity. 12713643 2003
Entrez Id: 10280
Gene Symbol: SIGMAR1
SIGMAR1 		0.300 Biomarker phenotype CTD_human Rimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transporters. 11684152 2001
Entrez Id: 54805
Gene Symbol: CNNM2
CNNM2 		0.300 Biomarker phenotype CTD_human Purification, crystallization and preliminary crystallographic analysis of the CBS-domain pair of cyclin M2 (CNNM2). 23027747 2012
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD 		0.300 Biomarker phenotype CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.300 Biomarker phenotype CTD_human Profound increase in sensitivity to glutamatergic- but not cholinergic agonist-induced seizures in transgenic mice with astrocyte production of IL-6. 12836160 2003